DENVER, CO and CORNWALL, UK, OCTOBER 25, 2010 – Research Instruments Limited (RI) today announced a new partnership with Modulation Optics, Inc., to develop a exclusive, highly sensitive optical system for Intracytoplasmic Morphologically-selected Sperm Injection (IMSI), which may lead to higher pregnancy rates following in vitro fertilization. Ensuring a high-sensitivity source imaging for maximum contract, this new offering, adapted from renowned Hoffman Modulation Contrast (HMC) technology, is an integral component of Research Instruments’ IMSI solution, designed for quick and easy routine clinical use.

IMSI is a modified form of the ICSI technique, injecting a single sperm into a single egg to achieve fertilization. However, with IMSI, sperm can be magnified 6,000 times more than in a conventional ICSI procedure, better enabling clinicians to identify the best quality sperm. Patients with severely low sperm count can benefit from IMSI.

The RI IMSI system is designed for use with the same microscope used for ICSI (Intracytoplasmic Sperm Injection), on standard plastic Petri dishes, thus maximising the clinical benefit of the technique, especially when viewing sperm. Research Instruments supplies this objective as part of a package including a high-sensitivity camera, medical-grade monitor and versatile imaging software. The RI IMSI system is also designed to be compatible with all popular inverted microscopes and micromanipulation systems.

"We are very proud to work in partnership with Modulation Optics, to develop the best possible technological solutions to real world challenges,” said David Lansdowne, Technical Director, Research Instruments. “We have seen the research on the IMSI technique and we believe that the only way to gain wider acceptance in clinical practice is by solving the practical issues associated with high magnification objectives.”

Current systems are expensive, time-consuming, difficult to work with, and are widely perceived to be too cumbersome for routine clinical application. Sperm samples degenerate rapidly so speed is very important.

“Modulation Optics is pleased to partner with Research Instruments to combine the imaging capabilities of high magnification Hoffman Modulation Contrast with RI’s outstanding product line for IMSI morphological screening,” said Bruce Phillips, Modulation Optics, New York. “The synergy of working to provide the best equipment for this exciting new application will only enhance a two-decade relationship of close and productive cooperation.”

About Research Instruments

Established in 1964, Research Instruments designs and manufactures IVF instruments and equipment for the world market, including cutting edge technology in IVF and the latest advances in biomedical equipment. The company is based in the United Kingdom, and distributes its products in over 62 countries worldwide. For more information, please visit www.research-instruments.com

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