Homepage  /  News

No difference in IVF success between frozen or fresh embryos

Shaoni Bhattacharya

Progress Educational Trust

25 June 2019

| | | |
[BioNews, London]

Reporting from the European Society for Human Reproduction and Embryology's 2019 annual meeting in Vienna

Freezing embryos for later implantation or using them fresh makes no difference to the success of IVF, according to a new study.

The so-called 'freeze-all' strategy has become increasingly popular in many fertility clinics as frozen embryo transfer is thought to reduce the risk of Ovarian Hyperstimulation Syndrome (OHSS) and improve IVF outcomes generally. 

'We found there's no indication for freeze-all embryo transfer for regular cycle women with no risk for OHSS,' said Dr Sacha Stormlund from Copenhagen University Hospital in Denmark. She presented the results of the large, randomised, controlled clinical trial at the annual meeting of the European Society for Human Reproduction and Embryology in Vienna, Austria on Monday.

In the study, some 460 patients at eight clinics across Denmark, Sweden and Spain had a single blastocyst transferred for IVF. A freeze-all approach was used in one group, with the frozen embryo transferred in a subsequent cycle. Fresh embryos were transferred in the other group.

The ongoing pregnancy rate following transfer was similar with both methods, as was the number of babies born through each method.

'I think we can now reasonably say, based on our results and those from other recent trials, that in normally ovulating patients there is no apparent benefit from a freeze-all strategy in IVF,' said Dr Stormlund. 

'However, the evidence derived from another large trial in women with polycystic ovary syndrome and at risk of responding excessively to stimulation suggests a considerable freeze-all benefit both in terms of live birth and ovarian hyperstimulation syndrome.'  

A spokesperson for the UK's Human Fertilisation and Embryology Authority said: 'Our most recent figures show that the use of frozen embryos has gone up by 11 percent since 2016, which indicates an increased uptake in freeze cycles.
 
'Frozen cycles' success rates at 23 percent have overtaken fresh embryo cycles' success rates (22 percent) for the first time since records began, meaning that patients can be reassured that freezing embryos can give them as much chance of success as fresh cycles.'

SOURCES & REFERENCES

RELATED ARTICLES FROM THE BIONEWS ARCHIVE

Success rates for IVF and ICSI in Europe plateau

25 June 2019 - by Shaoni Bhattacharya 
While IVF use in Europe has risen, the success rates after IVF or ICSI appear to have peaked...

IVF baby birth weights have been rising for 25 years

18 March 2019 - by Bernie Owusu-Yaw 
The average birth weight of babies conceived by IVF has increased by approximately 180 grams over a 25-year period, a UK study suggests...

'Freeze all' policy for embryos not always best for IVF

28 August 2018 - by Georgia Everett 
A study looking at whether frozen or fresh embryo transfers yield the best outcomes for IVF patients has found that the best technique varies from person to person, depending on their cycle so far...

Fresh embryos just as good as frozen for women without PCOS

15 January 2018 - by Georgia Everett 
Using fresh embryos in IVF gives the same chance of a live birth as using frozen embryos for ovulatory women, according to two new studies...



http://www.BioNews.org.uk
© Copyright Progress Educational Trust

Reproduced with permission from BioNews, an email and online sources of news, information and comment on assisted reproduction and genetics.

Share IVF News on FaceBook   Share IVF News on Twitter

Page Views: 494
Add to Favorites | Reply to Ad | Tell Your Friends
Date Added: 25 June 2019   Date Updated: 25 June 2019
Customer Reviews (0)
write a review
(No reviews found. You may write the first one!)


Join Our Newsletter - Don't Miss Anything!!!

Stay in touch with the latest news by subscribing to our regular email newsletters