Advancing the ART of Human Reproduction: Physiology and TechnologyCarole ChisholmSerono Symposia International, Inc.08 April 2005 |
Technological innovations and advances in genetics will enhance the ability to both evaluate and improve embryonic competence. This 3-day, in depth course will review what is known about the basic reproductive processes that represent rate-limiting steps in human reproduction. The participant will understand the full spectrum of these limits, starting by reviewing clinical data and extending fully through the molecular level. Methodologies currently being used to evaluate embryonic competence will be reviewed including technical requirements, biologic material, equipment, and personnel. Future technologies and screening strategies will then be presented, such that clinical reproductive endocrinologists, embryologists, and scientists will have a full understanding of the technologies as they become clinically available in the next several years. The course will provide opportunities to interact with expert faculty. In addition, two adjunct hands-on workshops in blastomere preparation for PGD are being offered.
TARGET AUDIENCE
Reproductive endocrinologists, embryologists, basic scientists, and other related health professionals will benefit from this course.
OBJECTIVES
At the conclusion of this program, the participant should be able to:
- Understand the genetic basis of human embryonic competence;
- Explain how epigenetic factors affect human development;
- Understand endometrial and oocyte determinants of implantation;
- Appreciate the limitations and promise of new technologies in IVF.
SCIENTIFIC COMMITTEE
Richard T. Scott, M.D., Scientific Chair
Reproductive Medicine Associates of New Jersey
Morristown, New Jersey, USA
Michael M. Alper, M.D.
Boston IVF and
Harvard Medical School
Waltham, Massachusetts, USA
ORGANIZING SECRETARY
Serono Symposia International, Inc.
1099 Hingham Street
Rockland, MA 02370 USA
Telephone 800-283-8088 or 781-681-2352
Fax: 781-681-2915
BLASTOMERE PREPARATION FOR PGD
HANDS-ON WORKSHOPS
An adjunct hands-on workshop session will be offered on Friday, May 13, 2005 from 5:30 pm to 9:30 pm. A second, concurrent, hands-on workshop session will be offered on Saturday, May 14, 2005 from 12:30 pm to 4:30 pm. Each workshop session is limited to 16 participants. The didactic portion of the workshop will address the theory and practice of preimplantation genetics in the IVF setting. The majority of the workshop will be spent in hands-on training in polar body, blastomere, and trophectoderm biopsy, cell spreading, and fixation techniques. Course participants will be acquainted with current equipment such as microscopes, micromanipulation equipment and laser system to incorporate biopsy and fixation techniques immediately into their IVF program. All work will be closely supervised by expert faculty. Workshop attendees will be provided with an additional syllabus with protocols and technical materials and either dinner (Friday) or lunch (Saturday), and refreshments. Microdissection equipment, display capability, and biopsy and fixation microscopes will be generously supplied by MidAtlantic Diagnostics, Inc.
SCIENTIFIC PROGRAM
Thursday, May 12, 2005
Plenary Session
Richard Scott, Session Chair
3:00 ? Registration
4:00 pm
4:00 pm Introductory Remarks
Richard Scott, Scientific Chair
4:15 pm Welcome Address
The Future of ART: What Are Our Most Critical Technologies and Issues?
Paul McDonough
5:15 pm Embryo Research: The Legal, Ethical, and
Regulatory Limitations
Alta Charo
6:00 pm ART and Multiple Gestation: Have We
Succeeded or Failed?
TBD
6:45 pm Welcome Reception
Friday, May 13, 2005
7:00 am Continental Breakfast (provided)
Session I ? Reproductive Competence
Gary Smith, Session Chair
8:00 am The Spin from Spindle Abnormalities and Meiotic Errors
David Keefe
8:45 am Is There More to Male Reproductive
Competence Than Fertilization?
Kathy Miller
9:30 am Embryo Fingerprinting: A Prospect for Embryo
Diagnosis
Richard Scott
10:15 am Break
Session II ? Laboratory Evaluation of Reproductive Competence
Douglas Powers, Session Chair
10:30 am Embryonic Development: An Awakening of Gene
Expression
Douglas Powers
11:15 am PGD: The Good, The Bad, and The Ugly
Richard Scott
11:45 am Embryo Morphology: More Than Meets the Eye?
Marlena Duke
12:30 pm Lunch
Session III ? Evolving Technologies in ART
Jason Barrit, Session Chair
2:00 pm In Vitro Maturation: Is It Mature Yet?
Gary Smith
2:45 pm Microfluidics: A New Biomedical Engineering Technique for ART
Gary Smith
3:30 pm Break
3:45 pm Oocyte Cryopreservation: Technologies, Safety, and Applications
Tom Toth
4:30 -
5:15 pm Ovarian Tissue Preservation: Challenges for the Future
Jacques Donnez
_________________________________________
5:30 ?
9:30 pm Blastomere Preparation for PGD
Hands-on Workshop
Saturday, May 14, 2005
7:00 am Continental Breakfast (provided)
Session IV ? Offspring from ART
Michael Alper, Session Chair
8:00 am Epigenetics: What the Genome Never Told Us
TBD
8:45am Imprinting Disorders in ART: Risk or Association?
James Toner
9:30 am Nuclear Transfer: Promise for the Future or
More Smoke and Mirrors?
Jason Barrit
10:15 am Break
10:30 am Can We Demonstrate that an Embryo is
Normal?
Marcelle Cedars
11:15 am Embryo Donation: What Are the Stumbling Blocks?
David Keefe
12:00 pm Lunch
_________________________________________
12:30 ?
4:30 pm Blastomere Preparation for PGD
Concurrent Hands-on Workshop
Session V ? Evaluating and Managing Endometrial Sufficiency
James Toner, Session Chair
1:30 am Assessing Implantation Potential
Richard Paulson
2:15 pm Non-Traditional Markers of Endometrial
Receptivity: Are They Ready For the Clinic?
Bruce Lessey
3:00 pm Break
3:15 pm Progesterone and ART: Fact and Fiction
James Toner
4:00 -
4:45 pm Beyond the HSG: New Imaging Technologies for
the Fertility Specialist
Elizabeth Puscheck
Sunday, May 15, 2005
7:00 am Continental Breakfast (provided)
Session VI ? Contemporary Issues in Follicular Stimulation
Richard Scott, Session Chair
8:00 am GnRH Antagonists: Are Outcomes Impacted?
Alan Copperman
8:45 am LH: Is There a Threshold and a Ceiling?
Zeev Shoham
9:30 am Break
Session VII ? Adjuncts for ART
Michael Alper, Session Chair
9:45 am How Can We Really Optimize IVF Outcomes?
Michael Alper
10:30 am Impact of Mental Health on ART Outcome: Strategies for Intervention
Alice Domar
11:15 am Acupuncture: The Yin and Yang for IVF
Michael Graubert
12:00 pm Closing Remarks
Michael Alper
Adjourn
This program is supported in part by an unrestricted educational grant from Serono, Inc.
All Serono Symposia International, Inc., programs are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of Serono Symposia International, Inc.
REGISTRATION FORM
Advancing the ART of Human Reproduction
May 12- 15, 2005
(Please type or print clearly)
_____________________________________________________
Last Name First Name M.I. Degree
_____________________________________________________
Institution
_____________________________________________________
Department
_____________________________________________________
Address
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City Province/State/Country Postal Code/Zip
_____________________________________________________
Office Telephone Fax Number
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E-Mail Address (Please print clearly)
____Advanced Full Registration US $550, prior to or on April 21, 2005
____ Full Registration US $650, after April 21, 2005
____ Advanced Trainee/Fellow Registration US $450*, prior to or on April 21, 2005
*Must be accompanied by a letter certifying status.
____ Trainee/Fellow Registration US $550*, after April 21, 2005
*Must be accompanied by a letter certifying status.
____ Guest Fee US $100**
**Guest includes friends and family members who accompany a full meeting registrant. Guests may attend all meals and social functions.
____________________________________________________
Guest Name (Last, First)
BLASTOMERE PREPARATION FOR PGD
HANDS-ON WORKSHOPS
____ Friday, May 13, 2005 US $150.
Workshop limited to first 16 participants. Dinner provided.
____ Saturday, May 14, 2005 US $150. Concurrent session.
Workshop limited to first 16 participants. Lunch provided.
____ Payment by check or money order
Payable to: Serono Symposia International, Inc.
Charge to the following Credit Card:
___ MasterCard ___ Visa ___ American Express
____________________________________________________
Card Number Exp. Date
If you require special assistance (wheelchair, auxiliary aids) or special dietary requirements, please indicate and we will contact you. ___ Yes
Mail or Fax to: Registrar: Advancing the ART
Serono Symposia International, Inc.
1099 Hingham Street
Rockland, MA 02370 USA
FAX 781-681-2915
Or you can register online at www.seronosymposia.org
SPEAKERS
Jason A. Barrit, Ph.D.
Reproductive Medicine Associates of New York
New York, New York, USA
Marcelle I. Cedars, M.D.
UCSF Women?s Health
Reproductive Endocrinology and Fertility
San Francisco, California, USA
R. Alta Charo, Ph.D.
University of Wisconsin Law School and
Department of Medical History and Bioethics
University of Wisconsin Medical School
Madison, Wisconsin, USA
Alan Copperman, M.D.
Reproductive Medicine Associates of New York
New York, New York, USA
Alice D. Domar, Ph.D.
Mind/Body Center for Women?s Health
Boston IVF
Waltham, Massachusetts, USA
Jacques Donnez, M.D., Ph.D.
Cliniques Universitaires Saint-Luc and
Catholic University of Louvain
Brussels, Belgium
Marlena Duke, MSc
Reproductive Medicine Associates of New York
New York, New York, USA
Michael D. Graubert, M.D.
Palmetto Fertility Center of South Florida
Miami, Florida, USA
David L.Keefe, M.D.
Division of Reproductive Medicine and Infertility
Women and Infants Hospital
Providence, Rhode Island, USA
and
Tufts - New England Medical Center
Division of Reproductive Medicine and Infertility
Department of Obstetrics and Gynecology
Boston, Massachusetts, USA
Bruce Lessey, Ph.D., M.D.
Department of Obstetrics and Gynecology
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, USA
Paul G. McDonough, M.D.
Medical College of Georgia
Department of Obstetrics and Gynecology
Augusta, Georgia, USA
Kathleen Miller, BCTS
Reproductive Medicine Associates of New Jersey
Morristown, New Jersey, USA
Richard J. Paulson, M.D.
Reproductive Endocrinology and Infertility Division
University of Southern California School of Medicine and
University of Southern California Infertility Center
Los Angeles, California, USA
R. Douglas Powers, Ph.D.
Boston IVF
Waltham, Massachusetts, USA, and
Boston College, and
Harvard Medical School
Boston, Massachusetts, USA
Elizabeth Puscheck, M.D.
Department of Obstetrics and Gynecology
Division of Reproductive Endocrinology and Infertility
Wayne State University School of Medicine
Detroit, Michigan, USA
Zeev Shoham (Schwart), M.D.
Reproductive Medicine and Infertility Unit
Kaplan Hospital
Rehovot, Israel
Gary D. Smith, Ph.D.
Department of Obstetrics and Gynecology
Reproductive Endocrinology and Infertility Division Assisted Reproductive Technologies Laboratory
University of Michigan Health System
Ann Arbor, Michigan, USA
James Toner, M.D., Ph.D.
Atlanta Center for Reproductive Medicine
Woodstock, Georgia, USA
Thomas L. Toth, M.D.
Vincent Memorial in Vitro Fertilization Unit
Massachusetts General Hospital
Boston, Massachusetts, USA
ACCREDITATION
Physician: Serono Symposia International, Inc., is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians.
Serono Symposia International, Inc., designates this educational activity for a maximum of 20.5 category I credits towards the AMA Physician?s Recognition Award. Four (4) additional category I credits may be claimed for workshop attendance. Each physician should claim only those credits that he/she actually spent in the educational activity.
Laboratory Professional: Application will be made to the American Board of Bioanalysis (ABB) for Professional Enrichment Education Renewal (PEER) contact hours.
OFFICIAL LANGUAGE
The official language of the Symposium is English.
REGISTRATION INFORMATION
The registration fee for Advancing the ART is US $550 on or before April 21, 2005 and US $650 after April 21, 2005 for a full registration. The registration fee is US $450 on or before April 21, 2005 and US $550 after April 21, 2005 for trainees, students, and fellows. This fee includes: all plenary sessions, three continental breakfasts, two lunches, one reception, refreshments, and course book.
BLASTOMERE PREPARATION FOR PGD
HANDS-ON WORKSHOPS
The registration fee for the hands-on workshop offered Friday, May 13, 2005 is US $150. The registration fee for the concurrent hands-on workshop offered Saturday, May 14, 2005 is US $150. This fee includes: one dinner (Friday) or lunch (Saturday), refreshments, and course materials. The workshop curricula are identical. Attendance at each workshop is limited to the first 16 participants.
Payments may be made by check, money order, American Express, MasterCard, or Visa. All completed registrations will be acknowledged by mail. Cancellations will be assessed a US $50 administrative fee and must be received no later than May 1, 2005.
LOCATION
Loews Miami Beach Hotel
1601 Collins Avenue
Miami Beach, Florida
33139
Tel: 305-604-1601
www.loews.com
HOTEL AND TRAVEL INFORMATION
Situated in the heart of the culturally diverse and fabulously hip art deco section of South Beach, the Loews Miami Beach Hotel offers innovative cuisine, efficient, friendly service and an elegant setting. Combined with sunshine, ocean breezes and a pristine beach, the hotel amenities include an oceanfront pool, private beach, in room internet access and a fitness center.
A limited block of rooms has been reserved for this meeting at a special rate of $229/night (single/double, USD) plus applicable tax, which is currently 13%. For reservations, telephone the hotel directly at Tel: 800-235-6397. We recommend that you register at the hotel early to secure a room. Reservations made after
April 21, 2005 are on a space-available basis.
AIR TRAVEL
We are pleased to offer discounted fares to our attendees through our air partner American Airlines. For your convenience, you may book these fares through your travel agent, or by calling our travel agent BTI/World Travel at 800-637-7872, or through American Airlines directly at 800-221-2255. Please be sure to mention the Meeting Index #17667 to take advantage of these low fares.
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