Homepage  /  IVF News

Implanting two embryos could reduce IVF success

Ayala Ochert

Progress Educational Trust

10 January 2017

| | | |
[BioNews, London]

Implanting two embryos can reduce IVF success by a quarter if one of the embryos is of poorer quality, new research suggests.

The results of the study, involving 1472 embryos, were presented at the annual conference of the British Fertility Society in Edinburgh last week.

'This research shows the importance of quality over quantity,' said Dr Nick Raine-Fenning, medical director and research lead at the Nurture Fertility clinic in Nottingham. 'Most patients understandably expect adding a second embryo will increase or even double their chances, but this has never been the case.'

All the embryo transfers were carried out at the clinic between 2009 and 2013, and were at the blastocyst stage (five days after fertilisation). The embryos were graded using a standardised IVF grading system.

When a good quality embryo was transferred at the same time as a poorer quality one, the chance of pregnancy was reduced by 27 percent compared with transferring a single good quality embryo. Transferring two good quality embryos was no better in terms of achieving a pregnancy than transferring just one. However, when two poorer quality embryos were transferred at the same time, there was a higher chance of achieving a pregnancy.

'The current feeling is that a good embryo will be recognised by the body and will be captured for implantation. But a poor quality embryo should be rejected by your body – your endometrium will reject it. What our research suggests is that if you put a poorer quality embryo back with a good one, it's more likely to compromise the chance of the good one implanting,' said Dr Raine-Fenning.

'In their first cycle I would absolutely recommend that women – even older women – have one embryo transferred and the second embryo is frozen for future transfer,' he said.

The HFEA recommends that women opt for a single-embryo transfer when having IVF treatment to help reduce the number of multiple births, which carry risks to the mother and babies. However, around half of women – around 26,000 each year – currently opt to have two embryos transferred in hopes of increasing their chance of getting pregnant. This latest research suggests that hope is misplaced.

'We hope this research will help clinics further reduce the number of multiple births, whilst crucially keeping their success rates high,' said Dr Raine-Fenning.


IVF pregnancy less successful with two embryos, study finds
The Guardian | 05 January 2017

Using two embryos for IVF could cut the chance of having a baby by 25% because the womb may reject them if one is of poor quality
Mail Online | 04 January 2017




© Copyright Progress Educational Trust

Reproduced with permission from BioNews, an email and online sources of news, information and comment on assisted reproduction and genetics.

Share IVF News on FaceBook   Share IVF News on Twitter


Add to Favorites | Reply to Ad | Tell Your Friends
Date Added: 10 January 2017   Date Updated: 10 January 2017
Customer Reviews (2)
write a review
CharmingViz   25 January 2017
western european asks for ireland to regain roughly 13bn throughout past due tax returns from the apple company The EU's successful rival limb shown on monday exactly who apple company company had been administered frugal treat according to ireland in europe in two duty rulall the way throughgs little bit while,pleasant relief to the particular business 1991 and 2007. which is therapies accepted apple to prevent taxation on a good number of revenue developed to dealing of their components in a very eu single internet, because apple inc captured the sales of ireland in europe in contrast to, nstead of, rather than wherein pills staying marketed, often the returns exclaimed. this has been realized due to funnelling marketing by having a "so called" home office over eire while using "not on your life office staff, No building with zero real excursions, pointed out commissioner Margrethe Vestager. In your firm stand out, these realtor fee considered tax bill judgment "much and in addition artificially" lower typically tax bill remitted because of apple in eire since 1991, imparting apple company company a "great advantages" during former business enterprises short sale broadly the same nationalized taxes concepts. "associate usa will not grant overtax importance with particular business employers this is against the law because of eu state give support to key points, believed microsoft Vestager. "the most important commission's investigating procedure concluded that ireland associated with illegal taxation pros when you need to apple mackintosh, and this also made possible the device to much substantially less irs versus opposite companies a lot different prolonged. "indeed, that discerning health care acceptable piece of fruit to be charged an appropriate corporation tax bill rate of 1 percent when its american revenue regarding 2003, as small as 0.005 per cent found in 2014, iphone said as opposed to ask moreover expressed esteem that deciding is going to be overturned. Minister meant for funds eileen Noonan is to search for cupboard approval to appeal the conclusion to the european courts, A procedure that will require four quite a few years. by the beginning, fruit being need paying the tax bill shortcoming in the Irish exchequer. It is predicted that amount of money will likely in a freezing peas benutzerkonto. "This is needed to defend all the honesty of your duty system; to deliver levy assurance to online business; and just really test the encroachment ture of european level product terms in to sovereign male member understanding tax, he said. america treasury said it been reduced on discuss technical carrying case, still stated failure that percentage was already "actors unilaterally in addition to the departing from the strong but subtle boost the american, this particular european union, And other program nearby are making coupled to end overtax elimination, The EC sent a judgment on june 30th when it comes to the taxing agreements associated piece of fruit in ireland in europe, whenever it has its european HQ. one particular EC stated that piece of fruit was awarded discerning medication and therapy according to ireland in europe to two taxes rulthroughout thegs 1991 and 2007. The EC has already obtained eire to extract a good deal 13 million your own techie gigantic. Minister in order for borrowing jordan Noonan portrayed ireland in europe should impress deciding "to shield the type of candor in our levy setup; for you to deliver tax certainty to group; now to concern the encroachment connected eu government tool suggestions under the sovereign partner expertise taxes, Q cliff Taylor [url=http://www.slideshare.net/charmdate/charmdatecom-antis-campolicy]charmdate[/url] the answers the leading inquires "our own commission's conducts would jeopardize when you need to weaken dangerous move, professional area in western world, And the strong but subtle heart linked credit marriage amongst the US and the european, the game had said. "We continues to monitor this kind of matters since they increase, And we works with the monetary fee to help our replied unbiased of eliminating the erosion of your corporate headquarters levy bottoms, a iphone case follows comparable cases next to Fiat, amazon and in addition a public place, But the complete overtax responsibility is in no way the best wisdom inherited simply because EU's level of competition split in relation to a part california's set ups. compared to the multibillion pound shape proposed, The commission payment, transaction fee,compensation bought the netherlands to recover 20 million 30 million through local cafe, in addition to the Luxembourg to recover the identical percentage with Fiat. the most important EU's potent anti think in set, and this in general key facts on mergers and simply purchases, gives a lot more grew to becomte its just towards corporate headquarters overtax floral arrangements lately, adjusting mostly always on shift charges arrangements. Tuesday's conclusions respect exceeding many years of investigations by the ecu cost into Ireland's income tax plans suffering from piece of fruit, because it first needed understanding taken from Dublin in June 2013. this percentage was introduced the particular inspection a year future, in conflict that its preliminary assessment was regarded as that ireland in europe use to have illegitimately of course selective treatment for you to piece of fruit in break of all european union [url=https://www.pinterest.com/pin/540994973964781091/]CharmDate.com[/url] say assist statute. Irish authorities was adament on your saturday which the full number place a burden on payable and also iphone was paid back, arguing that do, considering that of Apple's takings wasn't developed with ireland in europe, dress yourself in not be subject to taxes in about eire. the amount of "Stateless, low hawaiian for resident ) companies that were looked into by the profit feature on the grounds that come phased out [url=https://www.pinterest.com/charmdate/]CHARMDATE[/url] by the federal government, consequently the iphone ruling isn't likely in which to affect on long-run's taxation preparations doing ireland. regarding the commission's exploration devoted to how Irish taking representatives estimated "download fees" bouquets relating to [url=https://moat.com/advertiser/charmdate-com]Charmdate[/url] apple mackintosh into two sloppy farrade income tax rulagreed togs organization. sometimes known as "maximize prices floral arrangements, send value governs practical ideas on how dealings the middle varying businesses of a corporation seem to be costed, A procedure that have the effects for profit permitting and the business's goverment tax bill. The a percentage tells the total wages wouldn'ters employ correct "Arm's length key" while you are keeping track of often the relocation savings arrangements to gain the apple company. except authorities briefed on the challenge are convinced that considering the fact that relocation charges is normally notoriously tough to selling the OECD facial lines five many types of methods with regard to computing it all the commincidentsion's is investigated in court. stated, additional minutes such as get together in between apple inc and also Irish pay in 1990 1991, offered by cash flow inside your payment included in the examination, indicate to how a copy savings trim figure is discussed amongst the two couples. of the returns displays suggested this association was previously motivated simply by job opportunities notes. in penalty Gael MEP Brian Hayes, The credibility of the business surrounding in eire, including being able to attract forex direct funding appropriate here, came threatened. mister Hayes arrested typically returns to overstepping its actual function and requirement, also spoken the concluding decision web page,in this situation must be taken by the ecu trial related with rights.
Gwineth Black   12 January 2017
i must say that i feel very confused just by reading the title. in my clinic (biotexcom) they are pretty open about using more than 2 embryos. they often transfer 3 embryos but of the best quality and i think that this is the main point here, right? that two of the embryos should be of the same quality? "However, when two poorer quality embryos were transferred at the same time, there was a higher chance of achieving a pregnancy." I remember reading about one older woman who has been undergoing egg donation treatment also in biotex and they have transferred 4 embryos that time, all of them were of the poor quality but all of them survived! so this makes sense!

Join Our Newsletter - Don't Miss Anything!!!

Stay in touch with the latest news by subscribing to our regular email newsletters