IVF NewsWebinar: RBMO: EPISODE IV
International IVF Initiative 25 October 2021
RBMO: EPISODE IV Tuesday, 2nd November 2021 3PM EST/ 7PM GMT / 8PM CET [ Full Article ]  
News: Functional sperm developed in vitro from primate embryonic stem cells
Abbie Harper 25 October 2021
Stem cells from rhesus macaque monkeys have been used to make sperm in a lab. The study, published as a preproof paper in Fertility and Sterility Science, is the first to demonstrate making functional sperm cells in vitro using primate embryonic stem cells. As global rates of male infertility rise, the researchers at the University of Georgia in Athens, Georgia, have provided hope for future clinical therapies for infertility. 'This is a major breakthrough towards producing stem cell-based therapies to treat male infertility in cases where the men do not produce any viable stem cells,' noted lead researcher Dr Charles Easley, from the University of Georgia's College of Public Health. Rhesus macaque embryonic stem cells were used to generate sperm cells in the earlier stages of development, lacking a head and tail for swimming, known as spermatids. The spermatids were capable of fertilising a rhesus macaque egg in vitro. Scientists have previously produced sperm-like cells using mouse stem cells, but rhesus macaques are a more useful model for examining potential infertility therapies as they have a more similar reproductive mechanism to humans. Sarah Norcross director of the Progress Educational Trust, the charity that publishes BioNews, said: 'This is a significant step in establishing whether sperm created in the lab could, one day, be used for human reproduction. We will be watching closely as the researchers carry out this work in macaques, first seeing whether eggs fertilised with this type of sperm can lead to a pregnancy, and then seeing whether a pregnancy can be achieved with sperm derived from skin cells. Even if all of these things are achieved in macaques, it will still take many years and much more research before such techniques are fit for use in human treatments.' The research team plan to implant the embryos formed using in vitro spermatids into a surrogate rhesus macaque, to examine whether they can produce a healthy baby monkey. If successful, they intend to repeat the process using spermatid-like cells derived from macaque skin cells. SOURCES & REFERENCES
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Webinar: TUTORIALS IN CLINICAL EMBRYOLOGY
Marc Van den Bergh 20 October 2021
From 11th January 2022 Quartec GmbH organizes weekly 2 webinars to assist students in preparing their exams. This is a private initiative from Quartec GmbH and is not endorsed by any professional society or university.
Please register for 1. TUTORIAL IN CLINICAL EMBRYOLOGY : The cell and it's organelles on Jan 11, 2022 11:45 AM CET at: https://attendee.gotowebinar.com/register/8038870777851543568 After registering and payment you will receive a confirmation email containing information about joining the webinar.
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Announcement: Fetusday2021
[email protected] 19 October 2021
Jabalpur ObGyn society and Banerji research foundation call you for FetusCon2021. Getting pregnancy through fertility treatment and Having a healthy neonate is our aim of this annual meeting. Please join us for CME on Preimplantation and prenatal Genetics with early identification of sonographic anomalies in growing fetus with experts in Fertility treatment and Genetics [ Full Article ]
Webinar: REPORTS AND UPDATES
International IVF Initiative 19 October 2021
Tuesday 19th October, 2021. 3PM EST/ 8PM GMT / 9PM CET Presentations and discussions from industry leaders on what's new and upcoming! [ Full Article ]
News: Lack of Prss50 genes severely affects male fertility in mouse model
Dr Charlotte Douglas 19 October 2021
A gene previously unknown to have a role in fertility has been found to be essential for healthy sperm. Researchers from Baylor College of Medicine, Houston, Texas removed both copies of a gene called Prss50, which encodes an enzyme called Protease Prss50. Although the mice did produce sperm, the sperm had abnormal morphology, including bent, multiple, or missing tails. The male mice lacking both copies of Prss50 were severely subfertile. 'The sperm tail is important for fertility because it propels the sperm in its journey to fertilise the egg' explained corresponding author Dr Carolina Jorgez. During the process of healthy sperm development, certain genes are switched on and off periodically, allowing the sperm to mature. However, in mice lacking the Prss50 genes, this process appears to be disrupted. Instead, the early-development genes that should be switched off, have been incorrectly turned on. Publishing their findings in the journal Development, Dr Jorgez stated that 'the untimely activation of those genes is disrupting normal sperm development'. As well as being important for sperm development in mice, Prss50 was found to be highly active in human testes too, suggesting Prss50 may have a role in human fertility. In humans, infertility can affect approximately one in ten men. Of the men Dr Jorgez and her team studied, around 5 percent had dysfunctional Prss50 genes. Men with two dysfunctional copies of the Prss50 gene were infertile. Conversely, men that have one functional copy of Prss50 were fertile. Previous studies have often focused on the sperm head's role in infertility, not the tail. In the mice lacking Prss50, the sperm heads were generally unaffected. Notably however, the authors did find a very rare type of abnormal sperm occurring in 1 percent of cases; a head attached to either end of a single tail. This type of sperm abnormality has not been seen in humans, but the authors do not discount that this could exist. The authors envisage that understanding the genes responsible for healthy sperm will help with diagnosis and informing treatment. 'Our findings are a step towards identifying a panel of genes to screen for male infertility' said Dr Jorgez. SOURCES & REFERENCES
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Course: ART & Embryology training program
Chennai Fertility Center and Research Institute 12 October 2021
November 2021 training batch schedule - Nov 15th, 2021 - 29th Nov 2021 The International School of Embryology was established to offer training for clinicians in advanced reproductive technologies. Our skill and precision to all aspirants help them to know in-depth knowledge and experience. The members of our teaching faculty aim to bring doctors and embryologists to the highest level of knowledge about reproductive techniques and practical capability in the field. Our courses cover basics in Andrology, embryology, ICSI, and cryosciences (Hands-on). Limited Seats. For admission Contact 9003111598 [ Full Article ]
Webinar: CRYOGOVERNANCE IV
International IVF Initiative 07 October 2021
Tuesday 12th October, 2021. 3PM EST/ 8PM GMT / 9PM CET [ Full Article ]
Announcement: MICROPTIC Masterclass becomes established as a model in online education
MICROPTIC 07 October 2021
Microptic, specialized in biomedicine, introduced MICROPTIC Masterclass: a series of free webinars about different topics in order to disseminate quality knowledge to healthcare and lab professionals. After more than a year, MICROPTIC Masterclass is now a model in online education in the field of semen analysis and genetics. Periodically, the company organizes these live sessions, given by different experts, and with the possibility of asking and comment by attendees. Furthermore, all the video recordings are available on Microptic website for free. Standard courses In addition, Microptic offers training courses and workshops to professionals and distributors. This learning concept includes courses at different levels – taught by biologists – and hands-on training with fresh sample. Microptic training courses are customized to the needs and requirements of participants. For more information, visit: https://www.micropticsl.com/ [ Full Article ]
Webinar: I3 GOES MAVERICK
International IVF Initiative 01 October 2021
Tuesday 5th October, 2021. 3PM EST/ 8PM GMT / 9PM CET The Maverick Reproductive Biologists take over the International IVF Initiative's webinar this week! [ Full Article ]
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